DDx Generators and Symptom Checkers - Independent Reviews
A number of independent reviews of Differential Diagnostic Generators or Symptom Checkers have now appeared. Isabel has appeared at the top for all of them although we believe the reviewers should broaden their criteria to include other important aspects such as the ease and speed of use and ability to integrate into other electronic tools.
Differential Diagnosis Generators: an Evaluation of Currently Available Computer Programs
We identified evaluation criteria through consensus, applied these criteria to describe the features of DDX generators, and tested performance using cases from the New England Journal of Medicine (NEJM©) and the Medical Knowledge...
Bond, W.F., Schwartz, L.M., Weaver, K.R., Levick, D., Giuliano, M. & Graber, M.L., 2012. Differential diagnosis generators: an evaluation of currently available computer programs. Journal of General Internal Medicine, 27(2): 213–219. https://doi.org/10.1007/s11606-011-1804-8
The Effectiveness of Electronic Differential Diagnoses (DDX) Generators: A Systematic Review and Meta-Analysis
We conducted a systematic review and meta-analysis to investigate the efficacy and utility of DDX generators. We undertook a comprehensive search of the literature including 16 databases from inception...
Riches N, Panagioti M, Alam R, Cheraghi-Sohi S, Campbell S, Esmail A, et al. 2016. The Effectiveness of Electronic Differential Diagnoses (DDX) Generators: A Systematic Review and Meta-Analysis. PLoS ONE 11(3): e0148991. https://doi.org/10.1371/journal.pone.0148991
Evaluation of symptom checkers for self diagnosis and triage: audit study
For symptom checkers that provided a diagnosis, our main outcomes were whether the symptom checker listed the correct diagnosis first or within the first 20 potential diagnoses...
Semigran, H.L., Linder, J.A., Gidengil, C. & Mehrotra, A., 2015. Evaluation of symptom checkers for self diagnosis and triage: audit study. BMJ, 351, p.h3480. https://doi.org/10.1136/bmj.h3480







